Wholesale GLP 1 CAS 910463-68-2 Semaglutide Weight Loss GLP -1 Retatrutide High Purity Semiglutide Retatrutide 5mg 10mg
Products Name: Retatrutide
CAS No.: 2381089-83-2
Other Name: LY3437943 GIPR/GLP-1R
Purity: >99.0%
Molecular Formula: C225H348N48O68
Molecular Weight: 4813.527g/mol
Application: Weight loss
Appearance: White Lyophilized powder
Reconstitution: Required
Storage:After reconstitution store at 2°C - 8°C
Use: Inject
Specification: 5mg/vial and 10vials/box
What is Retatrutide ?
Retatrutide is the newest GLP-1R agonist and was approved by the FDA as a once-weekly injection for the treatment of T2DM in late 2017. The peptide is chemically similar to semaglutide,tirzepatide, with the inclusion of two structural modifications (Lau, Bloch, et al., 2015). The first is the replacement of Gly with the non-proteinogenic amino acid 2-aminoisobutyric acid (Aib) at position 2. The second is the attachment of octadecanoic diacid to the side chain of Lys-26 through a short polyethylene glycol (PEG) spacer and a γ-glutamic acid linker. The amino acid substitution renders the peptide more resistant to DPP-4 compared to liraglutide, and the presence of the 18-carbon fatty acid moiety results in a high binding affinity for serum albumin, which translates to a half-life of approximately 7 days in humans
Product Function:
- Helps slow food leaving your stomach
- Helps prevent your liver from making too much sugar
- Helps the pancreas produce more insul when your blood sugar levels are high
- Can help control blood glucose
- Can reduce hyperglycemia, especially after meals
- Can reduce fasting insul and fasting glucose
- Can reduce hemoglobin A1c
- Can decrease appetite and caloric intake, while inhibiting weight gain
- Has been shown to lower triglyceride levels and oxidative stress from high LDL
- Has been shown to help induce weight loss in obese patients with higher dosing
- Helps decrease leptin and increase leptin sensitivity
- Can increase the conversion of white fat to brown fat
How is Retatrutide different from Semaglutide and Trizepatide ?
Mechanism:
1. Semaglutide work as (GLP-1) hormone agonist.
2. Tirezepatide work as (GLP-1 & GIP ) hormone agonist.
3. Retatrutide work as (GLP-1 & GIP & Glucagon) hormones agonist.
Weight loss in trials:
1. Semaglutide led to a 6-12% reduction in body weight in 28 weeks
2. Tirezepatide led to a 15-20% reduction in body weight in 72 weeks
3. Retatrutide led to a 25% reduction in body weight in 48 weeks
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FAQ
1. How to make an order?
Send me inquiry here and let me know what you need with quantity
2. What's the lead time and shipping ways?
We will delivery to the package by USPS, FEDEX, DHL paket and YANWEN express to you after receive your payment, it would take around 15-18days to your address.
3. How do i keep the peptides when i receive it ?
Peptides in the form of lyophilized powder can be transported at room temperature by vacuum packaging, while polypeptides in the dissolved state need to be refrigerated at 2°C - 8°C. For long-term storage, peptides should be stored in the form of lyophilized powder store at -20°C or -80°C in a sealed container with desiccant, which can avoid the degradation of peptides to the greatest extent.
4. What's the payment methods ?
We could accept pay through paypal, western union, bank transfer and bitcoin.
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